Peeked Melanotan II
Anti-Aging Compound

Peeked Melanotan II

★★★★★
4.9 (256 reviews)
Copper Tripeptide-1 Glycyl-L-histidyl-L-lysine Copper C

Description Test

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Certificate of Analysis

Third Party Tested by Freedom Diagnostics
Latest
99.76%
Purity
Variant
GHK-Cu 50mg
Lot #
B1111
Labeled
50mg
Actual
59.26mg
Tested
Feb 4, 2026
View COA
Latest
99.54%
Purity
Variant
GHK-Cu 100mg
Lot #
B0111
Labeled
100mg
Actual
107.58mg
Tested
Feb 4, 2026
View COA
📈
70 %
Collagen increase
vs 50% vitamin C, 40% retinoic acid
🧬
31.2 %
Genes modulated
4,000+ human genes affected
🧑‍🦲
30-50 %
Hair growth
Follicle size increase
⏱️
12 weeks
Visible results
Clinical facial study duration
🧬

How GHK-Cu Works

The science, simplified

Multi-Pathway Regeneration

GHK-Cu is a naturally occurring tripeptide that binds with copper to create a powerful regenerative complex. Released from damaged collagen as an injury signal, it orchestrates healing by modulating thousands of genes involved in tissue repair, inflammation control, and cellular protection.

GE
Gene Expression
Primary
Upregulates 59% of affected genes Activates 47 DNA repair genes Suppresses inflammatory pathways
COL
Collagen Pathway
Strongest
Stimulates type I & III collagen Increases elastin production Enhances ECM remodeling
Cu²+
Copper Delivery
Supportive
Delivers copper to cells Activates SOD antioxidant Supports wound healing enzymes
Pickart & Margolina, Int J Mol Sci 2018
Key discovery

Unprecedented Gene Influence

GHK-Cu affects more human genes than any other studied peptide — modulating 31.2% of the human genome.

Research finding: GHK-Cu increased expression of 1,942 genes and suppressed 762 genes in human fibroblasts, affecting pathways from DNA repair to antioxidant defense.
Genes Upregulated 1,942
Genes Downregulated 762
DNA Repair Genes ↑ 47 genes
Antioxidant Genes ↑ 14 genes
📊

What Research Has Shown

Summary of clinical and preclinical findings
12-Week Facial Study — 71 Women
55.8 %
Wrinkle volume reduction

Wrinkle Reduction Comparison

GHK-Cu vs Control -55.8%
GHK-Cu vs Matrixyl® -31.6%
Placebo -0%
Trial details: 71 women with mild to advanced photoaging applied GHK-Cu facial cream twice daily for 12 weeks. Measurements included skin density, elasticity, and 3D wrinkle analysis.
Clinical outcomes
55.8 %
Wrinkle volume reduction

Key Trial Results

70% Research Participants Improved collagen production
55.8% Research Participants Wrinkle volume reduction
35.5% Research Participants Wrinkle depth decrease
Note: Results measured using 3D skin topography analysis and ultrasound imaging for objective assessment.
Comparison
55.8 %
Wrinkle volume reduction

Collagen Stimulation Comparison

GHK-Cu 70%
Vitamin C 50%
Retinoic Acid 40%
Note: Based on thigh skin biopsy studies measuring collagen production after 1 month of treatment.
Plasma Concentration Studies
55.8 %
Wrinkle volume reduction

Age-Related Decline in Natural GHK Levels

Age 20 -200 ng/mL
Age 40 -140 ng/mL
Age 60 -80 ng/mL
Age 80 -40 ng/mL
Pickart & Margolina 2018
✨

Beyond Skin Rejuvenation

Other benefits observed in research
Hair
Growth
30-50% follicle size increase
Hair Growth Studies
Wound
Healing
Enhanced diabetic ulcer healing
Mulder et al. 1994
47
DNA repair genes
Activated for cellular protection
Gene Expression Study
Anti
Inflammatory
Reduced TNF-α and IL-6
Campbell et al. 2012
Hair restoration

Follicle Regeneration

Follicle size increase +40%
Growth rate improvement +35%
Anagen phase extension +30%
Study finding: GHK-Cu increased hair follicle size by 30-50% compared to placebo in controlled studies.
Hair Growth Research
Wound healing

Tissue Repair Acceleration

Angiogenesis ↑ Enhanced
Fibroblast migration ↑ 70% faster
Collagen deposition ↑ Increased
Inflammatory response ↓ Reduced
Clinical evidence: Diabetic ulcer patients showed significantly improved healing with topical GHK-Cu treatment.
Wound Healing Studies
Gene modulation

Epigenetic Reprogramming

GHK-Cu acts as a master regulator of cellular health.

4,000+ Genes affected.

Follicle size increase +40%
Growth rate improvement +35%
Anagen phase extension +30%
Key insight: GHK-Cu shifts gene expression patterns from tissue destruction to tissue repair, affecting pathways involved in aging and regeneration.
Gene Expression Analysis
Antioxidant defense

Cellular Protection

SOD activity ↑ Increased
Catalase expression ↑ Enhanced
Free radical scavenging ↑ Improved
Lipid peroxidation ↓ 38%
Antioxidant Studies
⚠️

Safety Profile from Research

What clinical studies report

GHK-Cu has demonstrated an excellent safety profile across multiple studies with minimal adverse effects.

Common digestive issues

Generally Mild Side Effects

Across studies, adverse events were uncommon and typically mild when reported.

5%
Mild nausea
3%
Temporary irritation
Most symptoms resolved without intervention.
Theoretical concern

Copper Accumulation Risk

Copper toxicity is theoretically possible with extreme overuse but has not been reported in clinical studies.

Reported toxicity None in studies
Extreme overuse concern Theoretical only
Clinical safety signal Favorable

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